- Katherine Heigl as Tully Hart
- Sarah Chalke as Kate Mularkey
- Ben Lawson as Johnny Ryan
- Ali Skovbye as Teenage Tully
- Roan Curtis as Teenage Kate
- Laura Cerón as Isabel Brody
- Brandon Jay McLaren as Travis
- Jon Ecker as Max Brody
- Jenna Rosenow as Kimber Watts
- Kirsten Robek as Carol Mansour
- Patrick Sabongui as Professor Chad Wiley
- Marina Sofia Hernandez as Hope Brody
- Brendan Taylor as Mutt
- Forrest Anthony as Teenage Boy
- Raul Herrera as Father Ramon
- Mathias Retamal as Mando
- Hugo Raymundo as Stunt Soldier
- Marcel Zadeh as Officer
- Alec Santos as Mark Brody
- Michael Tiernan as Jake Brody
- Jonel Earl as Carol Stunt Double
- "He Is a Hustler" by Andrew Kingslow: The episode begins with Tully and Max having some loud sex as Kate listens in amazement.
- "No Matter What" by Badfinger: Kate and Tully enjoy a bicycle ride in the '70s timeline.
- "Hey Ya!" by Outkast: Tully plays cricket with Max and his family. The lyric "Don't want to meet your momma" suggests that Tully isn't quite ready for the moment.
- "Beri-Beri" by Kleenex LiLiPUT: Kate attends an art show with Mutt in the '80s timeline, and Tully discusses Johnny's recent behavior.
- "Every Song in Firefly Lane Season 1" ScreenRant February 4, 2021